Single molecule analyses of DNA in environmental microbes

submitted by: dougramsey
Comprehensive characterization of genomic composition in environmental microbial samples has been challenging, because the majority of microorganisms are difficult to culture. Additional challenges include a high degree of genetic diversity between and within species, various level of relative abundance and ubiquitous presence of cell-free DNA. Single cells or single molecules genomic assays hold great promise for tackling these challenges. Recent progresses in the developments of these...

Summary of Subgroup Discussions for Metagenomics 2008

submitted by: dougramsey

John Wooley of UC San Diego makes Closing Remarks for the Metagenomics 2008 Conference

Structural Genomics (SG) & Beginning a Research Dialogue with the Metagenomics Community

submitted by: dougramsey

Ian Wilson of The Scripps Research Institute & Stephen Burley, Eli Lilly & Co. Presents "Structural Genomics (SG) & Beginning a Research Dialogue with the Metagenomics Community"

Metaproteomics as a key technology for characterizing the human microbiome Nathan C. VerBerkmoes, Oak Ridge National Labs

submitted by: dougramsey
The human microbiome is a complex system of many microbial communities inhabiting a diversity of environmental niches throughout the human body. With at least an order of magnitude more cells and even greater diversity of genetic potential these microbial communities continually interact with the human host cells in complex but controlled manner that lead to normal human health. Our knowledge of the structure and function of these communities and the interactions with the human host is...

Genomic and Genetic Insight into Gut Microbiota Function and Manipulation

submitted by: dougramsey
Trillions of microbes live in our digestive tract and influence our biology in profound and diverse ways. Several diseases, including obesity and inflammatory bowel diseases, have been associated with large-scale shifts in microbiota composition. The ability to address basic questions concerning community function and plasticity are fundamental to understanding the extent of causal relationships between host biology and microbiota perturbations, and whether the microbiota is a viable...

TimeLogic

submitted by: dougramsey
Delivering the performance equivalent of hundreds to over one thousand CPU cores per accelerated node, the TimeLogic solutions are ideal for data-intensive next-generation genomics. Life science institutions worldwide have chosen the TimeLogic brand as their optimal solution for high-throughput bioinformatics. The DeCypher and CodeQuest biocomputing solutions blend proven bioinformatics algorithms with ultra-fast accelerator hardware to achieve a perfect combination of performance, accuracy,...