Microbial-mammalian metabolic cooperation is defined as the human ‘metabonome’. Transgenomic co-metabolic interactions within the metabonome greatly increase system complexity and this presents a significant challenge for elucidating the mechanisms by which the intestinal micro biome influences the host phenotype. By measuring and mathematically modelling changes in the levels of products of metabolism found in mammalian biological fluids and tissues, metabonomics offers fresh insight...
Molecular characterization of the bacterial flora in the lung of healthy, asthmatic and chronic obstructive pulmonary diseased (COPD) subjects Markus Hilty, Imperial College, London
