A Whole-Grain–Rich Diet Reduces Urinary Excretion of Markers of Protein Catabolism and Gut Microbiota Metabolism in Healthy Men after One Week

submitted by: Alastair Ross
Epidemiological studies consistently find that diets rich in whole-grain (WG) cereals lead to decreased risk of disease compared with refined grain (RG)-based diets. Aside from a greater amount of fiber and micronutrients, possible mechanisms for why WGs may be beneficial for health remain speculative. In an exploratory, randomized, researcherblinded, crossover trial, we measured metabolic profile differences between healthy participants eating a diet based on WGs compared with a diet...
Authors: Alastair Ross, Emma Pere-Trépat, Ivan Montoliu, Francois-Pierre Martin, Sebastiano Collino, Sofia Moco, Jean-Philippe Godin, Marilyn Cléroux, Philippe Guy, Isabelle Breton, Rodrigo Bibiloni, Anita Thorimbert, Isabelle Tavazzi, Lionel Tornier, Aude Bebuis, Stephen Bruce, Maurice Beaumont, Laurent-Bernard Fay, Sunil Kochhar

Healthy aging for the cancer patient

submitted by: mdanderson

“Being a senior does not necessarily mean that you’re old,” says Beatrice Edwards, M.D., associate professor in geriatric medicine at MD Anderson Cancer Center. “Yet, it’s important for elderly cancer patients to have their functional status evaluated in order to achieve successful cancer treatment outcomes.” In this podcast, Edwards shares tips on healthy aging for older adults and explains the role that a geriatrician can play in cancer treatment and survivorship.

Grape Powder Supplementation Prevents Oxidative Stress–Induced Anxiety-Like Behavior, Memory Impairment, and High Blood Pressure in Rats

submitted by: ssalim
We examined whether or not grape powder treatment ameliorates oxidative stress–induced anxiety-like behavior, memory impairment, and hypertension in rats. Oxidative stress in Sprague-Dawley rats was produced by using L-buthionine- (S,R)-sulfoximine (BSO). Four groups of rats were used: 1) control (C; injected with vehicle and provided with tap water), 2) grape powder–treated (GP; injected with vehicle and provided for 3 wk with 15 g/L grape powder dissolved in tap water), 3)...
Authors: Farida Allam, An Dao, Gaurav Chugh, Ritu Bohat, Faizan Jafri, Gaurav Patki, Christopher Mowrey, Mohammad Asghar, Karim Alkadhi, Samina Salim

Need for Greater Transparency in Enrollment in Drug Trials

submitted by: WentzMR

In an article appearing in the May 2013 issue of Mayo Clinic Proceedings, Dr. Mark A. Yarborough from the University of California, Davis, proposes the need to develop better disclosure, transparency, and measures of social value for persons recruited to participate in clinical research. Available at: http://tinyurl.com/d8appv7

Cardiovascular Fitness and Mortality After Contemporary Cardiac Rehabilitation

submitted by: WentzMR

Dr. James Stone, a Clinical Professor of Medicine at the University of Calgary, Canada, promotes the necessity, positive benefits, and overall mortality reduction with cardiac rehabilitation in patient with coronary artery disease as noted in their article appearing in the May 2013 issue of Mayo Clinic Proceedings. Available at: http://tinyurl.com/boopj26

Trust in Residents and Board Examinations: When Sharing Crosses the Boundary

submitted by: WentzMR
Dr. Gregory Ruhnke, an Assistant Professor in the Section of Hospital Medicine at the University of Chicago, in an article coauthored with Dr. David Doukas appearing in the May 2013 issue of Mayo Clinic Proceedings, examines the context and professional implications of residents preparing for board examinations using questions reproduced by previous residents. Available at: http://tinyurl.com/c5dhms6