Rethinking proteasome evolution: two novel bacterial proteasomes.

linked profile(s): Phil
submitted by: drnknmstrr
The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity: from HslV (heat shock locus v), which is encoded by 1 gene in bacteria, to the eukaryotic 20S proteasome, which is encoded by more than 14 genes. Despite this variation in complexity, all the proteasomes are composed of homologous subunits. We...
Authors: Valas Re, Bourne Pe

Anthony Komaroff (HHV-6 & 7 in CNS Dysfunction Session)

submitted by: hhv-6foundation

"Overview on HHV-6 and Chronic Fatigue Syndrome"
6th International Conference on HHV-6 & 7 in Baltimore, Maryland, USA
Day 3 - June 22, 2008 - HHV-6 & 7 in CNS Dysfunction Session

Janos Luka (Epidemiology & CIHHV-6 Session)

submitted by: hhv-6foundation

"Characterization of chromosomally integrated HHV-6A in a family with two out of four CIHHV-6 members symptomatic for CNS dysfunction"
6th International Conference on HHV-6 & 7 in Baltimore, Maryland, USA
Day 1 - June 20, 2008 - Epidemiology & CIHHV-6 Session

Peter Medveczky (Epidemiology & CIHHV-6 Session)

submitted by: hhv-6foundation

"Novel evidence indicates integration of unique human herpesvirus-6A DNA sequences into human chromosomes"
6th International Conference on HHV-6 & 7 in Baltimore, Maryland, USA
Day 1 - June 20, 2008 - Epidemiology & CIHHV-6 Session

Francesco Broccolo (Malignancy Session)

submitted by: hhv-6foundation

"Human herpesvirus-6 (HHV-6) etiopathogenetic role in development of cervical cancer by combining immunohistochemistry, laser microdissection and single cell-real-time PCR analysis"
6th International Conference on HHV-6 & 7 in Baltimore, Maryland, USA
Day 2 - June 21, 2008 - Malignancy Session

Aureile Lacriox (Malignancy Session)

submitted by: hhv-6foundation

"Detection and role of the DR7 oncoprotein from HHV-6 variant B in Reed-Sternberg cells of classical Hodgkin’s lymphoma"
6th International Conference on HHV-6 & 7 in Baltimore, Maryland, USA
Day 2 - June 21, 2008 - Malignancy Session