Background: Fatty acids in blood may be related to the risk of prostate cancer, but epidemiologic evidence is inconsistent. Blood fatty acids are correlated through shared food sources and common endogenous desaturation and elongation pathways. Studies of individual fatty acids cannot take this into account, but pattern analysis can. Treelet transform (TT) is a novel method that uses data correlation structures to derive sparse factors that explain variation. Objective: The objective...

AIM: To evaluate the effects of the adjunctive use of metronidazole (MTZ) or MTZ + amoxicillin (AMX) in the treatment of generalized chronic periodontitis (ChP). A secondary aim was to examine a possible added effect of chlorhexidine to these therapies. METHODS: One hundred and eighteen subjects received scaling and root planing (SRP) only or with MTZ [400 mg/thrice a day (TID)] or MTZ+AMX (500 mg/TID) for 14 days. Half of the subjects in each group rinsed with 0.12% chlorhexidine twice a...

In episode 65 of MicrobeWorld Video, Dr. Stan Maloy talks with Natalie Prystajecky Ph.D., Environmental Public Health Microbiologist, BCCDC Public Health Microbiology and Reference Laboratory, about her work with norovirus. This episode was filmed at the American Association for the Advancement of Science Meeting in Vancouver, Canada on February 16th, 2012. Norovirus is the leading cause of acute gastroenteritis in the world. In the U.S. norovirus accounts for up to sixty percent of all...

Aim: The aim of this study was to compare peri-implant conditions between fully edentulous (FES) and partially edentulous subjects (PES). Material and methods: A systematic review was conducted. The MEDLINE, EM- BASE and CENTRAL databases were searched for publications up to 1 January 2012. Studies reporting on the bleeding tendency of the peri-implant mucosa and/ or studies reporting on the prevalence of peri-implant mucositis and/or peri-im- plantitis were considered. Results:...

The Jewish majority and Arab minority populations in Israel exhibit disparities in nutrition-related chronic diseases, but comparative population-based dietary studies are lacking. We evaluated ethnic differences in dietary patterns in a population-based cross-sectional study of Arab and Jewish urban adults (n=1,104; aged 25-74 y). Dietary intake was assessed with an interviewer-administered quantified FFQ. We used principal-component analysis to identify 4 major dietary patterns: Ethnic,...

2nd Focus Lecture by Dr. Eduardo R. Mendoza, Visiting Scientist, Department of Membrane Chemistry, Max Planck Institute of Biochemistry, Germany and Senior Research Scientist, Faculty of Physics & Center for NanoScience, Ludwig Maximilian University, Munich, Germany. The lecture covered: (1) Understanding nanoparticle-cell interactions for nanosafety and nanomedicine, (2) A basic model of gold nanoparticles-cell interactions, (3) modelling targeted drug delivery with functionalized...