Genome-wide association study of chronic periodontitis in a general German population

submitted by: ateumer
Aim: To identify loci associated with chronic periodontitis through a genome wide association study (GWAS). Materials and Methods: A GWAS was performed in 4032 individuals of two independent cross-sectional studies of West Pomerania (SHIP n=3365 and SHIP-TREND n=667) with the different periodontal case definitions. Samples were genotyped with the Affymetrix Genome-Wide Human SNP Array 6.0 or the Illumina Human Omni 2.5 array. Imputation of the HapMap as well as the 1000 Genomes based...
Authors: A Teumer, B Holtfreter, U Völker, A Petersmann, M Nauck, R Biffar, H Völzke, HK Kroemer, P Meisel, G Homuth, T Kocher

A diet rich in high glucoraphanin broccoli interacts with genotype to reduce discordance in plasma metabolite profiles through modulating mitochondrial function

submitted by: Andrew Chapple
Background: Observational and experimental studies suggest that diets rich in cruciferous vegetables and glucosinolates may reduce the risk of cancer and cardiovascular disease (CVD). Objective: We tested the hypothesis that a 12-wk dietary intervention with high-glucoraphanin (HG) broccoli would modify biomarkers of CVD risk and plasma metabolite profiles to a greater extent than interventions with standard broccoli or peas. Design: Subjects were randomly assigned to consume 400 g...
Authors: Charlotte Armah, Maria Traka, Jack Dainty, Marianne Defernez, Astrid Janssens, Wing Leung, John Potter, Richard Mithen

Enhancing on the Usefulness and Maximizing the Utilization of Biological Collections in the University of the Philippines

submitted by: UP Los Baños

Documentation of the lecture on "Enhancing on the Usefulness and Maximizing the Utilization of Biological Collections in the University of the Philippines" by Dr. Salcedo Eduardo, Professor Emeritus, during the "Celebrating UPLB's Great Minds Lecture Series" on July 26, 2013 at the UPLB Operations Room, UPLB, College, Laguna

Fusion of Arts and Sciences: The Third Culture?

submitted by: UP Los Baños

Documentation of the lecture on "Fusion of Arts and Sciences: The Third Culture?" by Dr. Asuncion K. Raymundo, Professor Emeritus, during the "Celebrating UPLB's Great Minds Lecture Series" on July 26, 2013 at the UPLB Operations Room, UPLB, College, Laguna

Safety of Conventional and Biotech Food: How Safe is Safe?

submitted by: UP Los Baños

Documentation of the special seminar on Safety of Conventional and Biotech Food: How Safe is Safe? by Dr. Antonio C. Laurena
Research Professor, Crop Science Cluster-Institute of Plant Breeding, University of the Philippines Los Banos on June 20, 2013.

Diet, microbiota, and microbial metabolites in colon cancer risk in rural Africans and African Americans

submitted by: sjokeefe
Background: Epidemiologic studies have suggested that most cases of sporadic colon cancer can be attributed to diet. The recognition that colonic microbiota have a major influence on colonic health suggests that they might mediate colonic carcinogenesis. Objective: To examine the hypothesis that the influence of diet on colon cancer risk is mediated by the microbiota through their metabolites, we measured differences in colonic microbes and their metabolites in African Americans with a...
Authors: Junhai Ou, Franck Carbonero, Erwin G Zoetendal, James P DeLany, Mei Wang, Keith Newton, H Rex Gaskins, Stephen JD O’Keefe