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Some hereditary cancers might be preventable by compensating for the BRCA1 or BRCA2 gene mutations.

See our blog post at URL http://blog.openhelix.com/?p=10810 for more information on this resource. In today’s tip I will introduce you to another one of our efforts to “extend research” by showing you a glimpse of an OpenHelix app that we designed for the SciVerse platform from Elsevier. This app scans a ScienceDirect journal article for any database names or URLs that we train on, and then displays a list of such resources in the window of the app.

The digestive process transforms nutrients and bioactive compounds contained in food to physiologically active compounds. In vitro digestion systems have proven to be powerful tools for understanding and monitoring the complex transformation processes that take place during digestion. Moreover, the investigation of the physiological effects of certain nutrients demands an in vitro digestive process that is close to human physiology. In this study, human digestion was simulated with a 3-step...

The assessment of iron status where infections are common is complicated by the effects of inflammation on iron indicators and in this study we compared approaches that adjust for this influence. Blood was collected in 680 children (aged 6–35 mo) and indicators of iron status [(hemoglobin (Hb), zinc protoporphyrin (ZP), ferritin, transferrin receptor (TfR), and TfR/ferritin index)] and subclinical inflammation [(the acute phase proteins (APP) C-reactive protein (CRP), and a-1-acid...

In this video, Katherine Ververis (Epigenomic Medicine, Baker IDI Heart and Diabetes Institute), demonstrates how to extract nutrients from the florets of broccoli. We investigate the effects of broccoli extract on the viability on human erythroleukemic K562 cells. Broccoli evolved ~2000 years ago from a wild cabbage plant in Europe and since the Roman Empire it has been considered a uniquely valuable food among Italians. The word broccoli, is derived from the Italian plural of broccolo,...

"Science of NFL Football" is a 10-part video series funded by the National Science Foundation and produced in partnership with the National Football League. In this segment, NBC's Lester Holt looks at the physically demanding pre-season ritual of NFL training camp. Professor Douglas Casa, head of the Korey Stringer Institute at the University of Connecticut, and athletic trainers from the Pittsburgh Steelers explain what NFL players must do to stay hydrated and replenish the essential...