Lab for the Computer-Aided Discovery Methods course taught at Baylor College of Medicine. Design of an array CGH assay. Finding recurrent aberrations in breast cancer using publicly available array CGH data. Subtracting known human structural polymorphisms. Gene annotation to identify aberrations that involve genes known to be relevant for cancer progression. Identifying aberrations relevant for cancer progression by integrating DNA dosage and gene expression information.
The third cancer lecture for the Computer-Aided Discovery Methods course taught at Baylor College of Medicine. This lecture covers cancer stem cells, differentiation, metastasis, and cancer types by organ of origin.