Exploring Next Generation Sequencing Today

submitted by: dougramsey

Exploring Next Generation Sequencing Today, Thomas Jarvie, 454 Life Sciences

Computational Aspects of Metagenome Analysis

submitted by: dougramsey

Computational Aspects of Metagenome Analysis
Daniel Huson, Tuebingen University

Towards Computer Assisted Markup of Data: Habitat-Lite

submitted by: dougramsey
Lynette Hirschman, The MITRE Corporation Co-authors: Scott Mardis, Cheryl Clark, Kevin Cohen Habitat-Lite (aka EnvO-Lite) is a set of structured terms designed to facilitate capture of high-level information about habitat and sample source metadata for genomics and metagenomics samples. It is designed to be light-weight and compact. Habitat-Lite terms are drawn from the full EnvO ontology and are made avail able by the EnvO Consortium in the EnvO-Lite-GSC OBO file. Habitat-Lite terms include...

The Evolution of Small Bacterial Genomesin the Ultra-Oligotrophic Ocean

submitted by: dougramsey
The size and coding capacity of a genome are its most fundamental properties. What selective pressures deter mine the expansion and contraction of genomes, and how is genome size related to adaptive strategies? Very small marine microbial genomes are providing new insights into these questions. The first reports of genome sequences from the cyanobacterium Prochlorococcus and the α-proteo bacterium SAR11 (Pelagibacter) established that these very abundant marine bacterioplankton clades have...

Accessing the Metatranscriptome for Complex Marine Microbial Communities

submitted by: dougramsey
Sequencing the expressed genetic information of an ecosystem (metatranscriptome) can provide information about the response of organisms to varying environ mental conditions. Until recently, metatranscriptomics has been limited to microarray technology and random cloning methodologies. The application of high-throughput sequencing technology is now enabling access to both known and previously unknown transcripts in natural com munities. We present a study of a complex marine meta...

Genomic Standards Consortium Report

submitted by: dougramsey

Genomic Standards Consortium Report Dawn Field, Oxford Centre for Ecology and Hydrology