Moby, Legacy Apps and the Semantic Web

submitted by: nodrogluap
[Note: poor video quality lasts only for the first 30 seconds] Presentation given at the Web Services Biohackathon '08 in Tokyo, Japan 2008-02-11. It describes tools for using and providing interoperable bioinformatics Web services. This presentation followed another one outlining the (Bio)Moby protocol and its usage, see www.biomoby.org for more information. Presenter: Paul Gordon .

MELANOMA THERMOGRAPHY

submitted by: camdic

Thermography allows the investigator to create a 3 dimensional image based on infrared emissions from tissue. Warmer tissues show up as yellow and white, whereas darker colors represent cooler structures. Malignant tumors are metabolically active and appear yellow and white on the images.
Metastatic melanoma in left inguinal lymphonodes - metastatic melanoma in left leg -
Prof. Camillo O. Di Cicco, MD

Computational image analysis: from cells to tissues - Prof. Ioannis Kakadiaris

submitted by: ralanharris

Principles of image analysis. Segmentation, edge detection, and feature extraction. Imaging tissue section images obtained by H&E staining, immuno-histochemistry, and multi-color FISH. Part of the Computer-Aided Discovery Methods course taught at Baylor College of Medicine.

Protein interactions, targeted drug design, and pharmacogenetics - Prof. Timothy Palzkill

submitted by: ralanharris

Identifying protein interactions suitable for therapeutic intervention. Design of short peptides and peptidomimetics. Pharmacogenetics. Part of the Computer-Aided Discovery Methods course taught at Baylor College of Medicine.

Protein interaction networks - Prof. Yin Liu

submitted by: ralanharris

Inference of gene modules and protein interaction networks using using synthetic lethality method (e.g., Pan X et al, Cell 124 1069-1081, 2006) the yeast-two-hybrid method and homology with model organisms. Part of the Computer-Aided Discovery Methods course taught at Baylor College of Medicine.

Structural analysis of the evolution of steroid specificity in the mineralocorticoid and glucocorticoid receptors

submitted by: Michael Baker
Background The glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) evolved from a common ancestor. Still not completely understood is how specificity for glucocorticoids (e.g. cortisol) and mineralocorticoids (e.g. aldosterone) evolved in these receptors. Results Our analysis of several vertebrate GRs and MRs in the context of 3D structures of human GR and MR indicates that with the exception of skate GR, a cartilaginous fish, there is a...
Authors: Michael e Baker, Charlie Chandsawangbhuwana, Noah Ollikainen