Genome Variation at the Basepair Level - Prof. Aleks Milosavljevic

submitted by: ralanharris
Insights into cancer biology from the study of basepair-level changes in coding sequences. Genotyping vs. resequencing. Identifying cancer-related genes using association studies. Use of next-generation sequencing technologies to map chromosomal aberrations in cancer genomes. PCR-based resequencing vs. array-based enrichment. Using recurrence, pathway enrichment, and other signatures of positive selection to identify "driver" somatic mutations involved in cancer progression. Part of the...

aCGH Computational Lab - Jian Li

submitted by: ralanharris

Lab for the Computer-Aided Discovery Methods course taught at Baylor College of Medicine. Design of an array CGH assay. Finding recurrent aberrations in breast cancer using publicly available array CGH data. Subtracting known human structural polymorphisms. Gene annotation to identify aberrations that involve genes known to be relevant for cancer progression. Identifying aberrations relevant for cancer progression by integrating DNA dosage and gene expression information.

The 5th dimension

submitted by: akourakine

Introduction to the 5th dimension

Emperors of the Extreme

Emperor penguins can flourish in locales where few other animals roam. But scientists now wonder if they can adapt to a new threat: climate change.

Food Insufficiency Is Associated with High-Risk Sexual Behavior among Women in Botswana and Swaziland

submitted by: jeveleth
Background Both food insufficiency and HIV infection are major public health problems in sub-Saharan Africa, yet the impact of food insufficiency on HIV risk behavior has not been systematically investigated. We tested the hypothesis that food insufficiency is associated with HIV transmission behavior. Methods and Findings We studied the association between food insufficiency (not having enough food to eat over the previous 12 months) and inconsistent...
Authors: Sheri d Weiser, Karen Leiter, David r Bangsberg, Lisa m Butler, Fiona percy-de Korte, Zakhe Hlanze, Nthabiseng Phaladze, Vincent Iacopino, Michele Heisler

Personalized Medicine Symposium at SfN

submitted by: brainresource

Symposium on:
Brain-related Personalized Medecine
Held at Society for Neuroscience, 2007