biosights: October 29, 2012 - A stiff test for collectively migrating cells

submitted by: JCB
The mechanical properties of the extracellular matrix are known to regulate the migration of single cells, but whether substrate stiffness also affects collective cell migration is unclear. Ng et al. reveal that epithelial sheets move faster on stiffer matrices due to increased myosin contractility and mechanical coupling through cell-cell adhesions. This biosights episode presents the paper by Ng et al. from the October 29, 2012, issue of The Journal of Cell Biology and includes an...

20121106 - Protein Prediction 2 - Burkhard Rost - Introduction to Protein Function 2

submitted by: rostlab

Date: 20121106
Course: Protein Prediction 2
Title: Introduction to Protein Function 2
Speaker: Burkhard Rost

Glycolysis

submitted by: Qkaiser

An interactive group presentation of the process of glycolysis presented in front of a collegiate anatomy class.

The history of fluorescence microscopy

submitted by: LUMC_PA_MD
This video shows the history of fluorescence microscopy through the eyes of the eighty-two year Professor Johan Sebastiaan Ploem . Let him tell you about the nature and background of his inventions and his place in the history of microscopy. The current version is in Dutch, an English undertitled version will follow shortley. Deze video toont de geschiedenis van de fluorescentie microscopie door de ogen van de 82 jarige professor Johan Sebastiaan Ploem . Laat hem vertellen over de...

Dietary Selenium Deficiency Partially Rescues Type 2 Diabetes–Like Phenotypes of Glutathione Peroxidase-1–Overexpressing Male Mice

submitted by: xlei
This study was conducted to determine whether dietary Se deficiency precluded overproduction of glutathione peroxidase-1 (GPX1) activity in mice overexpressing (OE) this gene and thus rescued their type 2 diabetes–like phenotypes. A total of 20 male OE and wild-type (WT) mice were fed an Se-deficient (<0.02 mg/kg) diet or an Se-supplemented (0.3 mg/kg as sodium selenite) diet from 1 to 5 mo of age. Dietary Se deficiency eliminated or attenuated (P < 0.05) genotype differences in...
Authors: Xin Gen Lei, Li Li, Matt Pepper, Carol Roneker, Marko Vatamaniuk, Xi Yan

Quertle

submitted by: LitSearcher

Introduction to the Quertle biomedical literature search engine