A diet rich in high glucoraphanin broccoli interacts with genotype to reduce discordance in plasma metabolite profiles through modulating mitochondrial function

submitted by: Andrew Chapple
Background: Observational and experimental studies suggest that diets rich in cruciferous vegetables and glucosinolates may reduce the risk of cancer and cardiovascular disease (CVD). Objective: We tested the hypothesis that a 12-wk dietary intervention with high-glucoraphanin (HG) broccoli would modify biomarkers of CVD risk and plasma metabolite profiles to a greater extent than interventions with standard broccoli or peas. Design: Subjects were randomly assigned to consume 400 g...
Authors: Charlotte Armah, Maria Traka, Jack Dainty, Marianne Defernez, Astrid Janssens, Wing Leung, John Potter, Richard Mithen

Diet and exercise advice to reduce your cancer risk

submitted by: mdanderson
Download from iTunes: https://itunes.apple.com/us/itunes-u/diet-exercise-advice-to-reduce/id43... . Karen Basen-Engquist, Ph.D., professor in Behavioral Science and director of Energy Balance, works with patients at MD Anderson Cancer Center to change behaviors based on nutrition and physical activity. Basen-Engquist’s goal is to find the best psychological and social interventions to alter unhealthy behaviors that increase cancer risk. Listen to Basen-Engquist describe her research and...

Vitamin D for Health: A Global Perspective

submitted by: WentzMR
Dr. Michael Holick, a Professor of Medicine, Physiology and Biophysics from the Section of Endocrinology, Nutrition, and Diabetes, Vitamin D, Skin and Bone Research Laboratory at Boston University Medical Center, in Boston, MA, in an article appearing in the July 2013 issue of Mayo Clinic Proceedings, shares the value and role vitamin D plays throughout a person’s entire life in regard to bone health and non-skeletal health benefits that have been associated with reduced risk of many...

How to tell children their sibling has cancer

submitted by: mdanderson
Download from iTunes: https://itunes.apple.com/us/itunes-u/how-to-tell-children-their/id431848... . Pediatric cancer affects the whole family. Stress may cause parents to focus only on their ill child, forgetting that their other children need help coping with the new family dynamic brought about by cancer. Morgan Henry, a social work counselor at MD Anderson Cancer Center, shares important conversations to have with cancer patients’ siblings, including telling them their brother/sister...

Testicular cancer basics

submitted by: mdanderson
Download from iTunes: https://itunes.apple.com/us/itunes-u/testicular-cancer-basics/id43184821... Testicular cancer is the most common malignant cancer in males between the ages of 15 and 34, but it could strike at any age. Symptoms are not always obvious and self-examination is not a recommended way to screen for testicular cancer. Lance Pagliaro, M.D., professor in Genitourinary Medical Oncology at MD Anderson Cancer Center, discusses the basics, symptoms, diagnosis and treatment of...

Diet, microbiota, and microbial metabolites in colon cancer risk in rural Africans and African Americans

submitted by: sjokeefe
Background: Epidemiologic studies have suggested that most cases of sporadic colon cancer can be attributed to diet. The recognition that colonic microbiota have a major influence on colonic health suggests that they might mediate colonic carcinogenesis. Objective: To examine the hypothesis that the influence of diet on colon cancer risk is mediated by the microbiota through their metabolites, we measured differences in colonic microbes and their metabolites in African Americans with a...
Authors: Junhai Ou, Franck Carbonero, Erwin G Zoetendal, James P DeLany, Mei Wang, Keith Newton, H Rex Gaskins, Stephen JD O’Keefe