Computational image analysis: from cells to tissues - Prof. Ioannis Kakadiaris

submitted by: ralanharris

Principles of image analysis. Segmentation, edge detection, and feature extraction. Imaging tissue section images obtained by H&E staining, immuno-histochemistry, and multi-color FISH. Part of the Computer-Aided Discovery Methods course taught at Baylor College of Medicine.

Rosetta via GENIUS on the EUChinaGRID

submitted by: iSGTW

This video was produced by GILDA and INFN to show the use of Rosetta protein-folding software on the EUChinaGRID cyberinfrastructure via the GENIUS grid portal.

Microbial Observatory - Partners Video Magazine

submitted by: csrees
Researcher Jo Handelsman runs microbial observatories in Wisconsin and Alaska and studies underground microbes detrimental to healthy soil. Microbial Observatory is a segment from CSREES' Partners Video Magazine's 19th episode, The Soil Explorers. To view the entire episode, go to http://www.csrees.usda.gov/newsroom/partners/soil_explorers.html .

Antibody-protein interactions: benchmark datasets and prediction tools evaluation

linked profile(s): juliap
submitted by: apryl
Background The ability to predict antibody binding sites (aka antigenic determinants or B-cell epitopes) for a given protein is a precursor to new vaccine design and diagnostics. Among the various methods of B-cell epitope identification X-ray crystallography is one of the most reliable methods. Using these experimental data computational methods exist for B-cell epitope prediction. As the number of structures of antibody-protein complexes grows, further interest in prediction...
Authors: Julia v Ponomarenko, Philip e Bourne

Protein interactions, targeted drug design, and pharmacogenetics - Prof. Timothy Palzkill

submitted by: ralanharris

Identifying protein interactions suitable for therapeutic intervention. Design of short peptides and peptidomimetics. Pharmacogenetics. Part of the Computer-Aided Discovery Methods course taught at Baylor College of Medicine.

Protein interaction networks - Prof. Yin Liu

submitted by: ralanharris

Inference of gene modules and protein interaction networks using using synthetic lethality method (e.g., Pan X et al, Cell 124 1069-1081, 2006) the yeast-two-hybrid method and homology with model organisms. Part of the Computer-Aided Discovery Methods course taught at Baylor College of Medicine.