Modern Transportation and Infectious Disease – MWV15

submitted by: MicrobeWorld
From your local bus route to international air travel, infectious diseases can spread across the globe in a matter of hours. In this video podcast episode filmed at the Koshland Science Museum in Washington, D.C., Stephen Eubank from the Virginia Bioinformatics Institute of Virginia Tech and Daniel Lucey from Georgetown University discuss the role of transportation in the spread of disease and examine the effectiveness of various measures to curb transmission. Stephen Eubank, Ph.D., is a...

BIOTERRORISM: PLAGUE AS A BIOLOGICAL WEAPON

submitted by: camdic
Bioterrorism is the utilization of microorganisms or toxins in order to produce a disease and/or death in human beings, animals or plants. Different from conventional weaponry, relatively economic means are used that allow the elimination of living beings without destroying the surrounding atmosphere. The most probably method for spread of bioweapons is aerial transmission, continuing into water supplies and food. The CDC (US Centers for Disease Control and Prevention, Atlanta) has...

Cheminformatics in Open Notebook Science

submitted by: jcbradley

Jean-Claude Bradley guest lectures on Rajarshi Guha's cheminformatics course at Indiana University. After an introduction to Open Notebook Science and the synthesis of anti-malarial compounds, topics include SMILES, InChIs, InChIKeys, CMLRSS, JCAMP-DX, JSpecView, ExcelVBA, blogs, wikis and Second Life.

HUTCHINSON-GILFORD SYNDROME

submitted by: camdic

Recent studies suggest that, as in other aging syndromes, the Hutchinson-Gilford syndrome is due at to a defect in the mechanism of DNA repair. Mutations have been found in the Lamin A gene (LMNA) situated on chromosome 1.

LASSUEUR PICCARDI GRAHAM LITTLE Syndrome.

submitted by: camdic

A rare disease in which cicatricial (scarring) alopecia of the scalp is associated with widepsread keratosis pilaris particularly in the axillae and pubic area where scarring does not usually occur. The scarring in the scalp may be clinically indistinguishable from the end stage of other forms of scarring hair loss.(Abstract) Prof. Camillo O. Di Cicco,MD

Dynamic Remodeling of Individual Nucleosomes Across a Eukaryotic Genome in Response to Transcriptional Perturbation

submitted by: akshayb
The eukaryotic genome is packaged as chromatin with nucleosomes comprising its basic structural unit, but the detailed structure of chromatin and its dynamic remodeling in terms of individual nucleosome positions has not been completely defined experimentally for any genome. We used ultra-high–throughput sequencing to map the remodeling of individual nucleosomes throughout the yeast genome before and after a physiological perturbation that causes genome-wide transcriptional changes....
Authors: Sushma Shivaswamy, Akshay Bhinge, Yongjun Zhao, Steven Jones, Martin Hirst, Vishwanath r Iyer