Getting leads from Big Data

submitted by: OpenHelix

This video illustrates a search of the ICGC, International Cancer Genome Consortium, for a gene lost in tumor samples. For more details see the blog post: http://blog.openhelix.eu/?p=13404

Diet composition is associated with endogenous formation of N-nitroso compounds in obese men

submitted by: silviagratz
Endogenous formation of carcinogenic N-nitroso compounds (NOC) occurs in the human gut. Red meat is considered the most important dietary component linked to NOC formation, although nitrate and vitamin C (VitC) also contribute. We previously showed that high-protein weight-loss diets increased fecal NOC and this was enhanced by simultaneous carbohydrate restriction. Although previous studies have focused on the effect of either 1 or 2 dietary components on endogenous NOC formation, no...
Authors: Grietje Holtrop, Alexandra M. Johnstone, Claire Fyfe, Silvia W. Gratz

Scientists look at smokers' brain activity before and after quitting

submitted by: mdanderson

Francesco Versace, Ph.D., talks about "Error sensitivity as a predictor of nicotine abstinence and smoking cessation," a study he's leading at MD Anderson's Behavioral Research and Treatment Center, and a study participant shares his experiences.

Multiple myeloma – blood cancer formed in bone marrow

submitted by: mdanderson

Multiple myeloma is a cancer caused by malignant plasma cells. Plasma cells help the human body fight infection, but when they multiply out of control, the myeloma cells overpower the bone’s healthy cells causing harmful side effects; such as bone fractures and infections. Sheeba Thomas, M.D., assistant professor in Lymphoma/Myeloma at MD Anderson Cancer Center, discusses the basics, risk factors, diagnosis and treatment options for this rare cancer.

Video Tip of the Week: Microbiome Resources From JGI

submitted by: OpenHelix

For more information about this resource, see our blog post at URL http://blog.openhelix.eu/?p=13147. We visit both IMG/M (IMG with Microbiome Samples) (briefly) and the Integrated Microbial Genomes-Human Microbiome Project, or IMG/HMP in today’s tip.

Mantle cell lymphoma: a non-Hodgkin's lymphoma

submitted by: mdanderson

Mantle cell lymphoma (MCL) is a rare form of blood cancer belonging to the disease group classified as non-Hodgkin's lymphoma. Only 3-6% of all non-Hodgkin’s lymphoma cases in the United States are MCL. Michael Wang, M.D., associate professor, and Jorge Romaguera, M.D., professor, both in Lymphoma/Myeloma at MD Anderson Cancer Center, discuss this disease that forms in the lymph node region known as the mantle zone.