Metabolic Syndrome as a Risk Factor for Barrett’s Esophagus

submitted by: WentzMR

Noting a 2-fold increase in risk of Barrett’s Esophagus, Dr. Cadman Leggett, a fellow in gastroenterology at Mayo Clinic in Rochester, MN, discusses his article appearing in the February 2013 issue of Mayo Clinic Proceedings which establishes an association between metabolic syndrome and esophageal cancer. Available at: http://tinyurl.com/arjjan7

Desmoid tumors – dangerous when not treated as cancer

submitted by: mdanderson
Download from iTunes: https://itunes.apple.com/us/podcast/desmoid-tumors-dangerous-when/id4318... . Desmoid tumors, also known as "aggressive fibromatosis," develop from fibroblasts which are found throughout the body. Desmoid tumors may become life threatening when they constrict vital organs such as kidneys, lungs or intestines. Some physicians consider desmoid tumors non-cancerous since they do not metastasize, but there is a danger of undertreating. Raphael Pollock, M.D., Ph.D.,...

Medical hypnosis assists with surgery and medical procedures

submitted by: mdanderson
Hypnosis is an artificially produced state of consciousness which allows for greater responsiveness to suggestion. Ian Lipski M.D., associate professor in Anesthesiology and Perioperative Medicine at MD Anderson Cancer Center, uses medical hypnosis to help patients manage cancer treatment side effects like anxiety, fear and pain. Medical hypnosis shifts the focus of power away from the medical staff and gives the patient control over his/her cognizance. Learn how Dr. Lipski helps patients...

Endothelin-1 is a transcriptional target of p53 in epidermal keratinocytes and regulates UV induced melanocyte homeostasis

submitted by: arup.indra
Keratinocytes contribute to melanocyte activity by influencing their microenvironment, in part, through secretion of paracrine factors. Here we discovered that p53 directly regulates Edn1 expression in epidermal keratinocytes and controls UV-induced melanocyte homeostasis. Selective ablation of EDN1 in murine epidermis (EDN1ep-/-) does not alter melanocyte homeostasis in newborn skin but decreases dermal melanocytes in adult skin. Results showed that keratinocytic EDN1 in a non-cell...
Authors: Daniel J. Coleman, Gitali Ganguli-Indra, Stephen Hyter, Arup Indra, Steven Ma, Gary F. Merrill, Masashi Yanagisawa

Multivitamin-multimineral supplementation and mortality: A meta-analysis of randomized controlled trials

submitted by: mpase
Background: Multivitamins are the most commonly used supplement in the developed world. Recent epidemiological findings suggest multivitamin use increases the risk of mortality. Objectives: We aimed to determine whether multivitamin-multimineral treatment, used for primary or secondary prevention, increases the risk of mortality in independently living adults. Methods: We performed a meta-analysis of randomized, controlled trials. Multiple electronic databases were systematically searched...
Authors: Helen Macpherson, Andrew Pipingas, Matthew Pase

Aptamer Data from Base Pair Biotechnologies

submitted by: BasePairBio

Aptamers have until recently been tightly held by IP restrictions, Base Pair Biotechnologies Founder Bill Jackson presents information and data they have generated on aptmers in diverse assays such as biosensor and lateral flow. Presentation is from the American Society for Cell Biology meeting Dec 16, 2012