biosights: October 28, 2013 - A framework for understanding muscle microtubules

submitted by: JCB
The microtubules of skeletal muscle fibers are arranged into an orthogonal grid, but how this network is formed is unknown. Oddoux et al. reveal that the network is built by dynamic microtubules nucleated from Golgi elements. This biosights episode presents the paper by Oddoux et al. from the October 28, 2013, issue of The Journal of Cell Biology and includes an interview with senior author Evelyn Ralston (NIH, Bethesda, MD). Produced by Caitlin Sedwick and Ben Short. See the associated...

biosights: September 30, 2013 - The nodal network

submitted by: JCB
In addition to specialized actin structures such as lamellipodia and stress fibers, cells are thought to contain a contractile actomyosin matrix that maintains cell shape. Luo et al. describe the organization and dynamics of an actomyosin network that may fulfill this function. This network is formed by actin nodes that contain the formin DAAM1 and the crosslinker filamin A, and that are connected to each other by myosin II. This biosights episode presents the paper by Luo et al. from the...

The Nature Explorers Chiricahua Part 12 of 12

submitted by: thenatureexplorers

Chiricahua is a "Sky Island" region that supports a variety of wildlife, some of which are more commonly thought of as denizens of subtropical habitats in Mexico or Central America. Even in February with snow and temperatures as low as -10°F we still found a cornucopia of nature, turkeys, woodpeckers, centipedes, pines, yuccas, agaves, and more.

The Nature Explorers Chiricahua Part 11 of 12

submitted by: thenatureexplorers

Chiricahua is a "Sky Island" region that supports a variety of wildlife, some of which are more commonly thought of as denizens of subtropical habitats in Mexico or Central America. Even in February with snow and temperatures as low as -10°F we still found a cornucopia of nature, turkeys, woodpeckers, centipedes, pines, yuccas, agaves, and more.

The Nature Explorers Chiricahua Part 9 of 12

submitted by: thenatureexplorers

Chiricahua is a "Sky Island" region that supports a variety of wildlife, some of which are more commonly thought of as denizens of subtropical habitats in Mexico or Central America. Even in February with snow and temperatures as low as -10°F we still found a cornucopia of nature, turkeys, woodpeckers, centipedes, pines, yuccas, agaves, and more.

biosights: September 2, 2013 - Shrinking microtubules pull the centrosome into place

submitted by: JCB
When a T cell encounters a target antigen-presenting cell, it moves its centrosome to the immunological synapse that connects the two cells. Yi et al. reveal that centrosome repositioning is a biphasic process driven by the dynein-dependent capture and depolymerization of microtubules. This biosights episode presents the paper by Yi et al. from the September 2, 2013, issue of The Journal of Cell Biology and includes an interview with senior author John Hammer (NHLBI, Bethesda, MD). Produced...