XERODERMA PIGMENTOSUM

submitted by: camdic
Hereditary disease, trasmitted with recessive autosomical modality, the XP is characterized from extreme photosensivity, that causes strict and premature damages to level of the cutis and of the eyes. Its incidence is of 1: 250 thousand in Europe and USA, while in Japan the relationship is of 1:40 thousand. In the child affected by XP, also short exposure to the sun's ultraviolet rays, determines severe cutaneous sunburn with slow resolution, therefore it is from avoiding sources of...

Atoms to X-rays: How Do Proteins Fold? Theory Meets Experiments

submitted by: video_collector
The machinery of life depends on proteins--large organic molecules composed of tens, hundreds or even thousands of amino acids bound together and folded into specifically shaped structures. How they fold into these three-dimensional structures is known as the second genetic code and is one of great challenges in science today. Join UCSD biophysicist Jose Onuchic, as he explores how physics, chemistry, biology and mathematics are all being applied to crack the protein folding mystery. Series:...

Trudy Forte presents "Drugs for Brain Tumors"

submitted by: video_collector

Trudy Forte discusses her work developing nano-sized low-density lipoprotein (LDL) particles that can be used as a safe and effective means of delivering anticancer drugs to brain tumors, particularly the most common malignant brain tumor in adults and one of the deadliest forms of cancer. Series: Lawrence Berkeley National Laboratory Summer Lecture Series [Health and Medicine] [Science] [Show ID: 13002]

Modern Transportation and Infectious Disease – MWV15

submitted by: MicrobeWorld
From your local bus route to international air travel, infectious diseases can spread across the globe in a matter of hours. In this video podcast episode filmed at the Koshland Science Museum in Washington, D.C., Stephen Eubank from the Virginia Bioinformatics Institute of Virginia Tech and Daniel Lucey from Georgetown University discuss the role of transportation in the spread of disease and examine the effectiveness of various measures to curb transmission. Stephen Eubank, Ph.D., is a...

Interview with Computational Biologist and SciVee Cofounder Phil Bourne

linked profile(s): simont
submitted by: Phil

Prof. Simon Twigger of the Medical College of Wisconsin asked me to visit for a day in January of 2008. We started the day with this interview which Simon conducted which describes my career and interests. He kindly let us post it here. It might be of interest to anyone considering a career in computational biology as it covers one such career path which began before the field itself was established.

Dynamic Remodeling of Individual Nucleosomes Across a Eukaryotic Genome in Response to Transcriptional Perturbation

submitted by: akshayb
The eukaryotic genome is packaged as chromatin with nucleosomes comprising its basic structural unit, but the detailed structure of chromatin and its dynamic remodeling in terms of individual nucleosome positions has not been completely defined experimentally for any genome. We used ultra-high–throughput sequencing to map the remodeling of individual nucleosomes throughout the yeast genome before and after a physiological perturbation that causes genome-wide transcriptional changes....
Authors: Sushma Shivaswamy, Akshay Bhinge, Yongjun Zhao, Steven Jones, Martin Hirst, Vishwanath r Iyer