biosights: July 7, 2014 - The fluid dynamics of collective cell migration

submitted by: JCB
During development and tumor metastasis, cells prepare to migrate by undergoing an epithelial-to-mesenchymal transition that loosens their connections to neighboring cells. But some cell types then migrate en masse to their final destinations, indicating that their intercellular adhesions aren't disrupted completely. Kuriyama et al. reveal that the phospholipid lysophosphatidic acid promotes the collective migration of Xenopus neural crest cells by downregulating the surface expression of...

PharmGenEd™ Principles and Concepts of Pharmacogenomics

submitted by: KuoOffice

The presentation is divided into several sections as outlined by the powerpoint slide. In this module we will include the basic concepts of pharmacogenomics, ethical, legal, social issues, and a brief introduction of the PharmGenEd program.

Topological Defects in Soft Matter: Simulation Models and Applications, I

submitted by: icamvid

Topological Defects in Soft Matter: Simulation Models and Applications, I by Robin Selinger, Kent State University

I-CAMP 2014 - PANEL Discussion

submitted by: icamvid

I-CAMP 2014 - PANEL Discussion

biosights: June 9, 2014 - Rab18 tilts the balance of ER structure

submitted by: JCB
The endoplasmic reticulum consists of peripheral tubular networks connected to sheet-like domains surrounding the nucleus. Gerondopoulos et al. reveal that the Rab3GAP complex, which is mutated in the neurodevelopmental disorder Warburg Micro Syndrome, is a guanine nucleotide exchange factor that activates the small GTPase Rab18 (also mutated in Warburg Micro Syndrome) to control the balance between ER tubules and sheets. This biosights episode presents the paper by Gerondopoulos et al. from...

Paraplegic will walk again wearing exoskeleton at the World Cup

submitted by: nsf

Built with funding for basic research from the National Science Foundation, Dr. Miguel Nicolelis and the Walk Again Project have built an exoskeleton that will allow paraplegics to walk again. The exoskeleton uses computer algorithms to interpret the user's brain activity, which powers the exoskeleton forward.