biosights: July 8, 2013 - Vinculin delivers a clutch performance

submitted by: JCB
At the leading edge of migrating cells, actin assembly and membrane protrusion are closely coupled with the formation of integrin-based focal adhesions that attach to the extracellular matrix. Thievessen et al. reveal that the focal adhesion protein vinculin acts as part of a molecular clutch that engages actin flow to coordinate actin and focal adhesion dynamics. This biosights episode presents the paper by Thievessen et al. from the July 8, 2013, issue of The Journal of Cell Biology and...

Diet, microbiota, and microbial metabolites in colon cancer risk in rural Africans and African Americans

submitted by: sjokeefe
Background: Epidemiologic studies have suggested that most cases of sporadic colon cancer can be attributed to diet. The recognition that colonic microbiota have a major influence on colonic health suggests that they might mediate colonic carcinogenesis. Objective: To examine the hypothesis that the influence of diet on colon cancer risk is mediated by the microbiota through their metabolites, we measured differences in colonic microbes and their metabolites in African Americans with a...
Authors: Junhai Ou, Franck Carbonero, Erwin G Zoetendal, James P DeLany, Mei Wang, Keith Newton, H Rex Gaskins, Stephen JD O’Keefe

Disparity in embrasure fill and papilla height between tooth- and implant-borne fixed restorations in the anterior maxilla: a cross-sectional study

submitted by: jacosyn
Purpose: The objective of the present study was to compare interproximal fill and papilla height between different embrasures. Material and methods: One hundred and fifty non-smoking consecutive patients (mean age 54, range 32–73; 63 males and 87 females) without periodontal disease were selected in a multidisciplinary practice during regular supportive care. All had been treated for multiple tooth loss in the anterior maxilla at least one year earlier by means of a fixed restoration on...
Authors: Jan Cosyn, Hugo De Bruyn

20130625 - Protein Prediction 1 - Burkhard Rost - Transmembrane beta strands, solvent accessibility, 2D prediction

submitted by: rostlab

Date: 20130625

Course: Protein Prediction 1

Title: Transmembrane beta strands, solvent accessibility, 2D prediction

Speaker: Burkhard Rost

Audience: Computational Biology students

20130625 - Protein Prediction 1 - Burkhard Rost - Transmembrane beta strands, solvent accessibility, 2D prediction

submitted by: rostlab

Date: 20130625

Course: Protein Prediction 1

Title: Transmembrane beta strands, solvent accessibility, 2D prediction

Speaker: Burkhard Rost

Audience: Computer Science students

A videoscope for use in minimally invasive periodontal surgery

submitted by: skharrel
Abstract Introduction: Minimally invasive periodontal procedures have been reported to produce excellent clinical results. Visualization during minimally invasive procedures has traditionally been obtained by the use of surgical telescopes, surgical microscopes, glass fibre endoscopes or a combination of these devices. All of these methods for visualization are less than fully satisfactory due to problems with access, magnification and blurred imaging. Clinical Innovation: A...
Authors: SK Harrel, TG Wilson Jr, F Rivera-Hidalgo