Background: Epidemiologic studies have suggested that most cases of sporadic colon cancer can be attributed to diet. The recognition
that colonic microbiota have a major influence on colonic health suggests that they might mediate colonic carcinogenesis.
Objective: To examine the hypothesis that the influence of diet on colon cancer risk is mediated by the microbiota through their metabolites, we measured differences in colonic microbes and their metabolites in African Americans with a...
Authors: Junhai Ou, Franck Carbonero, Erwin G Zoetendal, James P DeLany, Mei Wang, Keith Newton, H Rex Gaskins, Stephen JD O’Keefe